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PFN1 Antikörper (C-Term)

PFN1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6264161
  • Target Alle PFN1 Antikörper anzeigen
    PFN1 (Profilin 1 (PFN1))
    Bindungsspezifität
    • 14
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 56
    • 32
    • 30
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 63
    • 5
    Kaninchen
    Klonalität
    • 53
    • 15
    Polyklonal
    Konjugat
    • 27
    • 8
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Dieser PFN1 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 21
    • 14
    • 13
    • 11
    • 11
    • 9
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Spezifität
    Profilin 1 Antibody detects endogenous levels of total Profilin 1.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human Profilin 1, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
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    Discover our top product PFN1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    PFN1 (Profilin 1 (PFN1))
    Andere Bezeichnung
    PFN1 (PFN1 Produkte)
    Synonyme
    GmPRO1 antikoerper, GmPRO2 antikoerper, PRO1 antikoerper, Profilin-1 antikoerper, profilin-1 antikoerper, profilin antikoerper, MGC130883 antikoerper, Profilin1 antikoerper, XProfilin1 antikoerper, sb:cb813 antikoerper, wu:fa91a03 antikoerper, ALS18 antikoerper, Pfn antikoerper, F6F22.21 antikoerper, F6F22_21 antikoerper, PFN1 antikoerper, PROFILIN 1 antikoerper, profilin 1 antikoerper, profilin antikoerper, profilin 1 antikoerper, profilin 1 L homeolog antikoerper, profilin homolog 1 antikoerper, Profilin-1 antikoerper, PRO2 antikoerper, PFN1 antikoerper, pfn1.L antikoerper, pfn1 antikoerper, Pfn1 antikoerper, PRF1 antikoerper, prf1 antikoerper, pfn-1 antikoerper
    Hintergrund

    Description: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.

    Gene: PFN1

    Molekulargewicht
    15kDa
    Gen-ID
    5216
    UniProt
    P07737
    Pathways
    Regulation of Actin Filament Polymerization, Tube Formation, Maintenance of Protein Location
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