PCSK2 Antikörper (AA 318-346)

Produktnummer ABIN5531693

Produktdetails anti-PCSK2 Antikörper

Target: PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))

Bindungsspezifität: AA 318-346

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCSK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This PCSK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-346 amino acids from the Central region of human PCSK2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PCSK2

Target: PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))

Andere Bezeichnung: PCSK2 (PCSK2 Produkte)

Synonyme: NEC 2 antikoerper, NEC-2 antikoerper, NEC2 antikoerper, PC2 antikoerper, SPC2 antikoerper, PCSK2 antikoerper, 6330411F23Rik antikoerper, AI839700 antikoerper, Nec-2 antikoerper, Nec2 antikoerper, Phpp-2 antikoerper, pc2 antikoerper, nec2 antikoerper, spc2 antikoerper, pcsk2 antikoerper, pcsk2-A antikoerper, proprotein convertase subtilisin/kexin type 2 antikoerper, proprotein convertase subtilisin/kexin type 2 L homeolog antikoerper, PCSK2 antikoerper, pcsk2 antikoerper, Pcsk2 antikoerper, pcsk2.L antikoerper

Hintergrund: PCSK2 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This protein is a proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. The protein is also known to cleave proopiomelanocortin, proenkephalin, prodynorphin and proluteinizing-hormone-releasing hormone.

Molekulargewicht: 71 kDa

Gen-ID: 5126

UniProt: P16519

Pathways: Peptide Hormone Metabolism, cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity