Ketohexokinase Antikörper (C-Term)

Produktnummer ABIN5531508

Produktdetails anti-Ketohexokinase Antikörper

Target: Ketohexokinase (KHK)

Bindungsspezifität: AA 251-281, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ketohexokinase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This Ketohexokinase (KHK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-281 amino acids from the C-terminal region of human Ketohexokinase (KHK).

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Ketohexokinase

Target: Ketohexokinase (KHK)

Andere Bezeichnung: Ketohexokinase (KHK Produkte)

Synonyme: wu:fj68h03 antikoerper, zgc:92219 antikoerper, zgc:92626 antikoerper, KHK antikoerper, khk antikoerper, KETHPRO antikoerper, ketohexokinase antikoerper, Ketohexokinase antikoerper, KHK antikoerper, khk antikoerper, Hhal_0921 antikoerper, AaeL_AAEL006316 antikoerper, Nwat_0240 antikoerper, Khk antikoerper

Hintergrund: Ketohexokinase (KHK), or fructokinase, catalyzes conversion of fructose to fructose-1-phosphate. Splice variant 1 is the highly active form found in liver, renal cortex, and small intestine, while splice variant 2 is the lower activity form found in most other tissues. KHK, like glucokinase (GCK) and glucokinase regulator (GCKR), is present in both liver and pancreatic islets. The inhibition of GCK by GCKR is blocked by binding of fructose-1-phosphate to GCKR. The chromosomal proximity of the metabolically connected GCKR and KHK genes has a genetic linkage in type 2 diabetes. Fructosuria, or hepatic fructokinase deficiency, is a benign, asymptomatic defect of intermediary metabolism associated with heterozygosity for G50R and A43T mutations in KHK.

Molekulargewicht: 33 kDa

Gen-ID: 3795

UniProt: P50053