IBTK Antikörper (AA 586-613)

Produktnummer ABIN5531459

Produktdetails anti-IBTK Antikörper

Target: IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))

Bindungsspezifität: AA 586-613

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IBTK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IBTK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-613 amino acids from the Central region of human IBTK.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.43 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu IBTK

Target: IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))

Andere Bezeichnung: IBTK (IBTK Produkte)

Synonyme: IBTK antikoerper, fi40c08 antikoerper, wu:fi40c08 antikoerper, DKFZp468J085 antikoerper, BTBD26 antikoerper, BTKI antikoerper, RP1-93K22.1 antikoerper, 5430411K16Rik antikoerper, AA409502 antikoerper, mKIAA1417 antikoerper, inhibitor of Bruton tyrosine kinase antikoerper, inhibitor of Bruton agammaglobulinemia tyrosine kinase antikoerper, inhibitor of Bruton tyrosine kinase L homeolog antikoerper, IBTK antikoerper, ibtk antikoerper, Ibtk antikoerper, ibtk.L antikoerper

Hintergrund: The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription.

Molekulargewicht: 151 kDa

Gen-ID: 25998

UniProt: Q9P2D0