HIRA Antikörper (N-Term)

Produktnummer ABIN5531345

Produktdetails anti-HIRA Antikörper

Target: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Bindungsspezifität: AA 32-61, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HIRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HIRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human HIRA.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu HIRA

Target: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Andere Bezeichnung: HIRA (HIRA Produkte)

Synonyme: HIRA antikoerper, wu:fb97b07 antikoerper, wu:fi43b08 antikoerper, si:ch211-188g24.3 antikoerper, AA138857 antikoerper, D16Ertd95e antikoerper, N28177 antikoerper, Tuple1 antikoerper, DGCR1 antikoerper, TUP1 antikoerper, TUPLE1 antikoerper, dgcr1 antikoerper, hira-A antikoerper, tup1 antikoerper, tuple1 antikoerper, homolog of histone chaperone HIRA antikoerper, histone cell cycle regulator antikoerper, histone cell cycle regulator a antikoerper, protein HIRA antikoerper, HIR histone cell cycle regulation defective homolog A (S. cerevisiae) antikoerper, HIRA antikoerper, histone cell cycle regulator S homeolog antikoerper, histone chaperone HIRA-like protein antikoerper, Tuple1/HirA antikoerper, HIRA antikoerper, hira antikoerper, LOC100052845 antikoerper, LOC100352472 antikoerper, LOC100407742 antikoerper, LOC100450459 antikoerper, LOC100467668 antikoerper, LOC100581135 antikoerper, LOC486424 antikoerper, Hira antikoerper, LOC732736 antikoerper, hira.S antikoerper

Hintergrund: This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.

Molekulargewicht: 112 kDa

Gen-ID: 7290

UniProt: P54198

Pathways: Chromatin Binding