HIRA Produkte
(HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
Kategorien
This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008].
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Ausgewählte HIRA Kategorien
HIRA Antikörper
High quality antibodies with extensive validation data.
HIRA Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene HIRA Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC
Validierungen
- (5)
Kat. Nr.
ABIN6141776
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC
Validierungen
- (4)
Kat. Nr.
ABIN7264499
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, FACS
Validierungen
- (4)
Kat. Nr.
ABIN1490946
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene HIRA Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1306658
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1306657
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3092925
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren HIRA Produkten
: "Nucleosome assembly is required for nuclear pore complex assembly in mouse zygotes." in: Nature structural & molecular biology, Vol. 21, Issue 7, pp. 609-16, (2014) (PubMed).: "HP1-mediated formation of alternative lengthening of telomeres-associated PML bodies requires HIRA but not ASF1a." in: PLoS ONE, Vol. 6, Issue 2, pp. e17036, (2011) (PubMed).
: "Molecular dissection of formation of senescence-associated heterochromatin foci." in: Molecular and cellular biology, Vol. 27, Issue 6, pp. 2343-58, (2007) (PubMed).
: "Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly." in: Nature structural & molecular biology, Vol. 13, Issue 10, pp. 921-9, (2006) (PubMed).
: "Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: coupling protein O-GlcNAcylation to transcriptional repression." in: Cell, Vol. 110, Issue 1, pp. 69-80, (2002) (PubMed).
: "Recruitment of the yeast Tup1p-Ssn6p repressor is associated with localized decreases in histone acetylation." in: The Journal of biological chemistry, Vol. 276, Issue 3, pp. 1808-13, (2001) (PubMed).
: "Ssn6-Tup1 interacts with class I histone deacetylases required for repression." in: Genes & development, Vol. 14, Issue 21, pp. 2737-44, (2000) (PubMed).
Synonyme und alternative Namen zu HIRA
histone cell cycle regulator (HIRA), histone cell cycle regulator a (hira), protein HIRA (LOC100052845), protein HIRA (LOC100352472), HIR histone cell cycle regulation defective homolog A (S. cerevisiae) (HIRA), protein HIRA (LOC100407742), protein HIRA (LOC100450459), protein HIRA (LOC100467668), protein HIRA (LOC100581135), protein HIRA (LOC486424), histone cell cycle regulator (Hira), HIRA (LOC732736), histone cell cycle regulator S homeolog (hira.S), histone chaperone HIRA-like protein (HIRA), Tuple1/HirA (hira), AA138857, D16Ertd95e, DGCR1, dgcr1, HIRA, hira-A, homolog of histone chaperone HIRA, N28177, si:ch211-188g24.3, TUP1, tup1, Tuple1, TUPLE1, tuple1, wu:fb97b07, wu:fi43b08Bezeichner auf Proteinebene für HIRA
- HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- fb97b07
- HIR histone cell cycle regulation defective homolog A-like
- protein HIRA-like
- histone cell cycle regulation defective homolog A
- protein HIRA
- TUP1-like enhancer of split protein 1
- cHIRA
- histone regulator protein
- TUP1-like enhancer of split gene 1
- DiGeorge critical region gene 1
- HIR histone cell cycle regulation defective homolog A
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