ARHGEF11 Antikörper (AA 605-632)

Produktnummer ABIN5531285

Produktdetails anti-ARHGEF11 Antikörper

Target: ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))

Bindungsspezifität: AA 605-632

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ARHGEF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 605-632 amino acids from the Central region of human ARHGEF11.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ARHGEF11

Target: ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))

Andere Bezeichnung: ARHGEF11 (ARHGEF11 Produkte)

Synonyme: ARHGEF11 antikoerper, GTRAP48 antikoerper, PDZ-RHOGEF antikoerper, B930073M02 antikoerper, E130307F09 antikoerper, PDZ-RhoGEF antikoerper, Prg antikoerper, RhoGEF antikoerper, mKIAA0380 antikoerper, Gtrap48 antikoerper, Rho guanine nucleotide exchange factor (GEF) 11 antikoerper, Rho guanine nucleotide exchange factor 11 antikoerper, rho guanine nucleotide exchange factor 11 antikoerper, arhgef11 antikoerper, ARHGEF11 antikoerper, Arhgef11 antikoerper, LOC511220 antikoerper

Hintergrund: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.

Molekulargewicht: 168 kDa

Gen-ID: 9826

UniProt: O15085

Pathways: Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling