ARHGEF11 Antikörper
Kurzübersicht für ARHGEF11 Antikörper (ABIN7242893)
Target
Alle ARHGEF11 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Synthetic peptide of human ARHGEF11
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.8 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))
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Andere Bezeichnung
- ARHGEF11
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Hintergrund
- Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.
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Molekulargewicht
- 168 kDa
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NCBI Accession
- NP_055599
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UniProt
- O15085
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Pathways
- Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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