E2F2 Antikörper (AA 258-286)

Produktnummer ABIN5531081

Produktdetails anti-E2F2 Antikörper

Target: E2F2 (E2F Transcription Factor 2 (E2F2))

Bindungsspezifität: AA 258-286

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser E2F2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This E2F2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-286 amino acids from the Central region of human E2F2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu E2F2

Target: E2F2 (E2F Transcription Factor 2 (E2F2))

Andere Bezeichnung: E2F2 (E2F2 Produkte)

Synonyme: E2F-2 antikoerper, CG1071 antikoerper, Dmel\\CG1071 antikoerper, E2F antikoerper, E2F2 antikoerper, dE2F-2 antikoerper, dE2F2 antikoerper, dE2f2 antikoerper, de2f2 antikoerper, e2f2 antikoerper, 9230110J10 antikoerper, E130207A07 antikoerper, fb40b03 antikoerper, wu:fb40b03 antikoerper, E2F transcription factor 2 antikoerper, si:ch211-160f23.5 antikoerper, E2F2 antikoerper, E2f2 antikoerper, si:ch211-160f23.5 antikoerper

Hintergrund: E2F2 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46 % amino acid identity to E2F1. [provided by RefSeq].

Molekulargewicht: 48 kDa

Gen-ID: 1870

UniProt: Q14209

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication