DUSP8 Antikörper (C-Term)

Produktnummer ABIN5531052

Produktdetails anti-DUSP8 Antikörper

Target: DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))

Bindungsspezifität: AA 456-487, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This DUSP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 456-487 amino acids from the C-terminal region of human DUSP8.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu DUSP8

Target: DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))

Andere Bezeichnung: DUSP8 (DUSP8 Produkte)

Synonyme: zgc:77593 antikoerper, C11orf81 antikoerper, HB5 antikoerper, HVH-5 antikoerper, HVH8 antikoerper, 5530400B01Rik antikoerper, AI593498 antikoerper, Nttp1 antikoerper, Hb5 antikoerper, M3/6 antikoerper, DUSP8 antikoerper, dual specificity phosphatase 8 antikoerper, dual specificity phosphatase 8a antikoerper, dual specificity protein phosphatase 8 antikoerper, DUSP8 antikoerper, dusp8 antikoerper, dusp8a antikoerper, DSP8 antikoerper, Dusp8 antikoerper, LOC615727 antikoerper

Hintergrund: DUSP8 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP8 inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin.

Molekulargewicht: 66 kDa

Gen-ID: 1850

UniProt: Q13202