DUSP8 Antikörper

Produktnummer ABIN7266849

Der Kaninchen Polyklonal anti-DUSP8 Antikörper (ABIN7266849) detektiert spezifisch DUSP8 in WB und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für DUSP8 Antikörper (ABIN7266849)

Target: DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-DUSP8 Antikörper

Verwendungszweck: DUSP8 Rabbit pAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human DUSP8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:1000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DUSP8

Target: DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))

Andere Bezeichnung: DUSP8

Hintergrund: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2.,DUSP8,C11orf81,HB5,HVH-5,HVH8,Signal Transduction,DUSP8

Molekulargewicht: 65kDa

Gen-ID: 1850

UniProt: Q13202