DUSP10 Antikörper (AA 204-232)
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- Target Alle DUSP10 Antikörper anzeigen
- DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
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Bindungsspezifität
- AA 204-232
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DUSP10 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This DUSP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-232 amino acids from the Central region of human DUSP10.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product DUSP10 Primärantikörper
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- Applikationshinweise
- For WB starting dilution is: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
- Andere Bezeichnung
- DUSP10 (DUSP10 Produkte)
- Synonyme
- DUSP10 antikoerper, MKP-5 antikoerper, MKP5 antikoerper, 2610306G15Rik antikoerper, AI158871 antikoerper, Mkp-5 antikoerper, Mkp5 antikoerper, dual specificity phosphatase 10 antikoerper, DUSP10 antikoerper, Dusp10 antikoerper
- Hintergrund
- Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique, it is evenly distributed in both the cytoplasm and the nucleus. This gene is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli. Three transcript variants encoding two different isoforms have been found for this gene.
- Molekulargewicht
- 53 kDa
- Gen-ID
- 11221
- UniProt
- Q9Y6W6
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