Aurora Kinase C Antikörper (AA 115-145)

Produktnummer ABIN5530433

Produktdetails anti-Aurora Kinase C Antikörper

Target: Aurora Kinase C (AURKC)

Bindungsspezifität: AA 115-145

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aurora Kinase C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Aurora-C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-145 amino acids from the Central region of human Aurora-C.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Aurora Kinase C

Target: Aurora Kinase C (AURKC)

Andere Bezeichnung: Aurora-C (AURKC Produkte)

Synonyme: AURKC antikoerper, AIE2 antikoerper, AIK3 antikoerper, ARK3 antikoerper, AurC antikoerper, SPGF5 antikoerper, STK13 antikoerper, aurora-C antikoerper, AIE1 antikoerper, ARK-3 antikoerper, IAK3 antikoerper, Stk13 antikoerper, aurora kinase C antikoerper, AURKC antikoerper, Aurkc antikoerper

Hintergrund: Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.

Molekulargewicht: 36 kDa

Gen-ID: 6795

UniProt: Q9UQB9

Pathways: Zellzyklus, Maintenance of Protein Location