AIRE Antikörper (AA 64-92)
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- Target Alle AIRE Antikörper anzeigen
- AIRE (Autoimmune Regulator (AIRE))
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Bindungsspezifität
- AA 64-92
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser AIRE Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This AIRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the Central region of human AIRE.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product AIRE Primärantikörper
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- Applikationshinweise
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For WB starting dilution is: 1:1000
For IF starting dilution is: 1:10~50 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- AIRE (Autoimmune Regulator (AIRE))
- Andere Bezeichnung
- AIRE (AIRE Produkte)
- Synonyme
- AIRE1 antikoerper, APECED antikoerper, APS1 antikoerper, APSI antikoerper, PGA1 antikoerper, autoimmune regulator antikoerper, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) antikoerper, AaeL_AAEL013794 antikoerper, CpipJ_CPIJ001208 antikoerper, CpipJ_CPIJ001209 antikoerper, AIRE antikoerper, Aire antikoerper
- Hintergrund
- This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).
- Molekulargewicht
- 58 kDa
- Gen-ID
- 326
- UniProt
- O43918
- Pathways
- Chromatin Binding
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