Syndecan 1 Antikörper (AA 23-254)

Produktnummer ABIN5518953

Produktdetails anti-Syndecan 1 Antikörper

Target: Syndecan 1 (SDC1)

Bindungsspezifität: AA 23-254

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Syndecan 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Syndecan-1(SDC1) detection. Tested with WB in Human.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Syndecan-1(SDC1) detection. Tested with WB in Human.
Gene Name: syndecan 1
Protein Name: Syndecan-1

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human Syndecan-1/SDC1 recombinant protein (Position: Q23-G254). Human Syndecan-1/SDC1 shares 69.2% and 69.8% amino acid (aa) sequence identity with mouse and rat Syndecan-1/SDC1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-Syndecan 1 Antikörper (ABIN5518953)

Huang, Zhu, Zhang, Zhu, Liu, Zhu, Wang, Li, Yang, Dong, Liu, Chen, Zhang, Yang, Deng, Fan, Wang, Liu, Ma, Fu, Wu: "S100+ cells: a new neuro-immune cross-talkers in lymph organs." in: Scientific reports, Vol. 3, pp. 1114, (2013) (PubMed).

Details zu Syndecan 1

Target: Syndecan 1 (SDC1)

Andere Bezeichnung: SDC1 (SDC1 Produkte)

Synonyme: CG10497 antikoerper, CT27296 antikoerper, Dmel\\CG10497 antikoerper, Dsyn antikoerper, Syd antikoerper, Syn antikoerper, dSdc antikoerper, l(2)10608 antikoerper, sdc antikoerper, syd antikoerper, syn antikoerper, Syn1 antikoerper, cd138 antikoerper, synd1 antikoerper, xSyn1 antikoerper, syndecan1 antikoerper, Syndecan-1 antikoerper, XSyndecan-1 antikoerper, SDC1 antikoerper, CD138 antikoerper, SDC antikoerper, SYND1 antikoerper, syndecan antikoerper, AA408134 antikoerper, AA409076 antikoerper, Sstn antikoerper, Synd antikoerper, Synd1 antikoerper, syn-1 antikoerper, HSPG antikoerper, SYNDECA antikoerper, Syndecan antikoerper, Syndecan antikoerper, syndecan 1 antikoerper, Sdc antikoerper, sdc1 antikoerper, SDC1 antikoerper, Sdc1 antikoerper

Hintergrund: Syndecan 1 is a protein which in humans is encoded by the SDC1 gene. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Synonyms: Syndecan-1, SYND1, CD138, SDC1, SDC

Gen-ID: 6382

UniProt: P18827

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism