REV1 Antikörper (C-Term)

Produktnummer ABIN5517785

Produktdetails anti-REV1 Antikörper

Target: REV1 (REV1, Polymerase (DNA Directed) (REV1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser REV1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: INLIALPAFS QVDPEVFAAL PAELQRELKA AYDQRQRQGE NSTHQQSASA

Produktmerkmale: This is a rabbit polyclonal antibody against REV1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human REV1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu REV1

Target: REV1 (REV1, Polymerase (DNA Directed) (REV1))

Andere Bezeichnung: REV1 (REV1 Produkte)

Synonyme: ARABIDOPSIS THALIANA HOMOLOG OF REVERSIONLESS 1 antikoerper, ATREV1 antikoerper, K23L20.9 antikoerper, K23L20_9 antikoerper, 1110027I23Rik antikoerper, AU022044 antikoerper, Rev1l antikoerper, REV1L antikoerper, DNA-directed DNA polymerase antikoerper, HIG1 hypoxia inducible domain family member 1C antikoerper, REV1, DNA directed polymerase antikoerper, REV1 antikoerper, HIGD1C antikoerper, Rev1 antikoerper

Hintergrund: This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. Two alternatively spliced transcript variants that encode different proteins have been found.

Alias Symbols: REV1, REV1L,

Protein Interaction Partner: RELA, POLD3, MSH2, REV3L, BRCA1, PCNA, MAD2L2, POLH, UBC, CDC27, REV1, POLK, POLI, C1orf86, MYC, HSP90AB1, HSP90AA1, POLDIP2, POLL, FHL2,

Protein Size: 1251

Gen-ID: 51455

NCBI Accession: XP_005264024

UniProt: Q9UBZ9

Pathways: DNA Reparatur, Regulation of Actin Filament Polymerization, Production of Molecular Mediator of Immune Response