ARABIDOPSIS THALIANA HOMOLOG OF REVERSIONLESS 1 antikoerper, ATREV1 antikoerper, K23L20.9 antikoerper, K23L20_9 antikoerper, 1110027I23Rik antikoerper, AU022044 antikoerper, Rev1l antikoerper, REV1L antikoerper, DNA-directed DNA polymerase antikoerper, HIG1 hypoxia inducible domain family member 1C antikoerper, REV1, DNA directed polymerase antikoerper, REV1 antikoerper, HIGD1C antikoerper, Rev1 antikoerper
Hintergrund
This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. Two alternatively spliced transcript variants that encode different proteins have been found.