RRAGA Antikörper (C-Term)

Produktnummer ABIN5517617

Produktdetails anti-RRAGA Antikörper

Target: RRAGA (Ras-Related GTP Binding A (RRAGA))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RRAGA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CKEQRDVHRF EKISNIIKQF KLSCSKLAAS FQSMEVRNSN FAAFIDIFTS

Produktmerkmale: This is a rabbit polyclonal antibody against RRAGA. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RRAGA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RRAGA

Target: RRAGA (Ras-Related GTP Binding A (RRAGA))

Andere Bezeichnung: RRAGA (RRAGA Produkte)

Synonyme: FIP-1 antikoerper, FIP1 antikoerper, RAGA antikoerper, 1300010C19Rik antikoerper, AI255374 antikoerper, Raga antikoerper, Ras related GTP binding A antikoerper, Ras-related GTP binding A antikoerper, RRAGA antikoerper, Rraga antikoerper

Hintergrund: RRAGA is a guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. It may play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. Also it may alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.

Alias Symbols: RRAGA,

Protein Interaction Partner: RRAGC, RPTOR, STAU1, UBC, IL7R, ASAP1, CPSF2, CPSF3, CPSF1, CSTF2T, PAPOLA, CPSF4, CSTF3, CDC73, LAMTOR1, NOL8, RRAGA, RRAGD,

Protein Size: 313

Gen-ID: 10670

NCBI Accession: NP_006561

UniProt: Q7L523