RRAGA Antikörper (AA 1-160)

Produktnummer ABIN7269878

Produktdetails anti-RRAGA Antikörper

Target: RRAGA (Ras-Related GTP Binding A (RRAGA))

Bindungsspezifität: AA 1-160

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RRAGA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: RRAGA Rabbit pAb

Sequenz: MPNTAMKKKV LLMGKSGSGK TSMRSIIFAN YIARDTRRLG ATIDVEHSHV RFLGNLVLNL WDCGGQDTFM ENYFTSQRDN IFRNVEVLIY VFDVESRELE KDMHYYQSCL EAILQNSPDA KIFCLVHKMD LVQEDQRDLI FKEREEDLRR LSRPLECACF

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human RRAGA (NP_006561.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RRAGA

Target: RRAGA (Ras-Related GTP Binding A (RRAGA))

Andere Bezeichnung: RRAGA (RRAGA Produkte)

Synonyme: FIP-1 antikoerper, FIP1 antikoerper, RAGA antikoerper, 1300010C19Rik antikoerper, AI255374 antikoerper, Raga antikoerper, Ras related GTP binding A antikoerper, Ras-related GTP binding A antikoerper, RRAGA antikoerper, Rraga antikoerper

Hintergrund: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death.,RRAGA,FIP-1,FIP1,RAGA,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,G protein signaling,Signal Transduction,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Endocrine & Metabolism,Regulator of mTOR complex function,Regulators,RRAGA

Molekulargewicht: 36kDa

Gen-ID: 10670

UniProt: Q7L523