MBTPS2 Antikörper (N-Term)

Produktnummer ABIN5517527

Produktdetails anti-MBTPS2 Antikörper

Target: MBTPS2 (Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MBTPS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VGGWTVVYLT DLVLKSSVYF KHSYEDWLEN NGLSISPFHI RWQTAVFNRA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MBTPS2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MBTPS2

Target: MBTPS2 (Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2))

Andere Bezeichnung: MBTPS2 (MBTPS2 Produkte)

Synonyme: BRESEK antikoerper, IFAP antikoerper, KFSDX antikoerper, S2P antikoerper, 9630032G22Rik antikoerper, AI662535 antikoerper, LRRGT00063 antikoerper, membrane bound transcription factor peptidase, site 2 antikoerper, membrane-bound transcription factor peptidase, site 2 antikoerper, MBTPS2 antikoerper, Mbtps2 antikoerper

Hintergrund: This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome), IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.

Alias Symbols: S2P, IFAP, KFSD, KFSDX, OLMSX, BRESEK

Protein Interaction Partner: UBC, ATF6B,

Protein Size: 519

Gen-ID: 51360

NCBI Accession: NM_015884, NP_056968

UniProt: O43462

Pathways: ER-Nucleus Signaling