MBTPS2 Antikörper (N-Term)

Produktnummer ABIN953342

Produktdetails anti-MBTPS2 Antikörper

Target: MBTPS2 (Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2))

Bindungsspezifität: AA 14-44, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MBTPS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human MBTPS2 (N-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 14-44 amino acids from the N-terminal region of human MBTPS2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MBTPS2

Target: MBTPS2 (Membrane-Bound Transcription Factor Peptidase, Site 2 (MBTPS2))

Andere Bezeichnung: MBTPS2 (MBTPS2 Produkte)

Synonyme: BRESEK antikoerper, IFAP antikoerper, KFSDX antikoerper, S2P antikoerper, 9630032G22Rik antikoerper, AI662535 antikoerper, LRRGT00063 antikoerper, membrane bound transcription factor peptidase, site 2 antikoerper, membrane-bound transcription factor peptidase, site 2 antikoerper, MBTPS2 antikoerper, Mbtps2 antikoerper

Hintergrund: This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome), IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.Synonyms: Membrane-bound transcription factor site-2 protease, S2P, S2P endopeptidas, Site-2 protease, Sterol regulatory element-binding proteins intramembrane protease

Molekulargewicht: 57444 Da

Gen-ID: 51360

NCBI Accession: NP_056968

Pathways: ER-Nucleus Signaling