STOML2 Antikörper (Middle Region)

Produktnummer ABIN5517342

Produktdetails anti-STOML2 Antikörper

Target: STOML2 (Stomatin (EPB72)-Like 2 (STOML2))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STOML2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LRIMDPYKAS YGVEDPEYAV TQLAQTTMRS ELGKLSLDKV FRERESLNAS

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle terminal region of human STOML2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu STOML2

Target: STOML2 (Stomatin (EPB72)-Like 2 (STOML2))

Andere Bezeichnung: STOML2 (STOML2 Produkte)

Synonyme: zgc:63505 antikoerper, MGC116533 antikoerper, 0610038F01Rik antikoerper, MSLP2 antikoerper, SLP-2 antikoerper, stomatin (EPB72)-like 2 antikoerper, stomatin like 2 antikoerper, stomatin like 2 L homeolog antikoerper, stomatin (Epb7.2)-like 2 antikoerper, stoml2 antikoerper, STOML2 antikoerper, stoml2.L antikoerper, Stoml2 antikoerper

Hintergrund: Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.

Alias Symbols: SLP-2, HSPC108

Protein Size: 356

Gen-ID: 30968

NCBI Accession: NM_001287031, NP_001273961

UniProt: Q9UJZ1

Pathways: SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion