MCM3 Antikörper (C-Term)

Produktnummer ABIN5517161

Produktdetails anti-MCM3 Antikörper

Target: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCM3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ETEDEEEKSQ EDQEQKRKRR KTRQPDAKDG DSYDPYDFSD TEEEMPQVHT

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MCM3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MCM3

Target: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Andere Bezeichnung: MCM3 (MCM3 Produkte)

Synonyme: HCC5 antikoerper, P1-MCM3 antikoerper, P1.h antikoerper, RLFB antikoerper, AL033361 antikoerper, C80350 antikoerper, Mcmd antikoerper, P1 antikoerper, p1.m antikoerper, cb32 antikoerper, chunp6867 antikoerper, wu:fa26g03 antikoerper, CG4206 antikoerper, DmMCM3 antikoerper, DmMcm3 antikoerper, DmeMCM3 antikoerper, Dmel\\CG4206 antikoerper, MCM3 antikoerper, McM3 antikoerper, Mcp-PCR2 antikoerper, PCR2 antikoerper, dMCM3 antikoerper, xmcm3 antikoerper, minichromosome maintenance complex component 3 antikoerper, MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) antikoerper, Minichromosome maintenance 3 antikoerper, minichromosome maintenance complex component 3 L homeolog antikoerper, MCM complex subunit Mcm3 antikoerper, MCM3 antikoerper, mcm3 antikoerper, Mcm3 antikoerper, mcm3.L antikoerper

Hintergrund: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: HCC5, P1.h, RLFB, P1-MCM3

Protein Size: 808

Gen-ID: 4172

NCBI Accession: NM_001270472, NP_001257401

UniProt: P25205

Pathways: DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA