MAML1 Antikörper (Middle Region)

Produktnummer ABIN5517154

Produktdetails anti-MAML1 Antikörper

Target: MAML1 (Mastermind-Like 1 (MAML1))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAML1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VNKSSPRPGG PYLQPSHVNL LSHQPPSNLN QNSANNQGSV LDYGNTKPLS

Produktmerkmale: This is a rabbit polyclonal antibody against MAML1. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human MAML1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAML1

Target: MAML1 (Mastermind-Like 1 (MAML1))

Andere Bezeichnung: MAML1 (MAML1 Produkte)

Synonyme: mam1 antikoerper, mam-1 antikoerper, xmam1 antikoerper, MAML1 antikoerper, AI644666 antikoerper, AW743257 antikoerper, D930008C07Rik antikoerper, Mam-1 antikoerper, Mam1 antikoerper, mKIAA0200 antikoerper, mastermind like transcriptional coactivator 1 L homeolog antikoerper, mastermind like transcriptional coactivator 1 antikoerper, mastermind like 1 (Drosophila) antikoerper, mastermind-like transcriptional coactivator 1 antikoerper, maml1.L antikoerper, MAML1 antikoerper, Maml1 antikoerper

Hintergrund: This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.

Alias Symbols: MAML1 {ECO:0000312|HGNC:HGNC:13632

Protein Interaction Partner: Su(H), NOTCH1, RBPJ, PBRM1, PHF8, SMARCA4, HDAC9, PIAS1, MAML1, CDK8, EP300, NOTCH3, NOTCH2, CREBBP, NOTCH4, MAML2, MAML3,

Protein Size: 1016

Gen-ID: 9794

NCBI Accession: NP_055572

UniProt: Q92585

Pathways: Notch Signalweg, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development