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MAML1 Antikörper (AA 1-45)

MAML1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7159033
  • Target Alle MAML1 Antikörper anzeigen
    MAML1 (Mastermind-Like 1 (MAML1))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-45
    Reaktivität
    • 29
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 28
    • 1
    • 1
    Kaninchen
    Klonalität
    • 30
    Polyklonal
    Konjugat
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser MAML1 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 20
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Mastermind-like protein 1 protein (1-45AA)
    Isotyp
    IgG
    Top Product
    Discover our top product MAML1 Primärantikörper
  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MAML1 (Mastermind-Like 1 (MAML1))
    Andere Bezeichnung
    MAML1 (MAML1 Produkte)
    Synonyme
    mam1 antikoerper, mam-1 antikoerper, xmam1 antikoerper, MAML1 antikoerper, AI644666 antikoerper, AW743257 antikoerper, D930008C07Rik antikoerper, Mam-1 antikoerper, Mam1 antikoerper, mKIAA0200 antikoerper, mastermind like transcriptional coactivator 1 L homeolog antikoerper, mastermind like transcriptional coactivator 1 antikoerper, mastermind like 1 (Drosophila) antikoerper, mastermind-like transcriptional coactivator 1 antikoerper, maml1.L antikoerper, MAML1 antikoerper, Maml1 antikoerper
    Hintergrund

    Background: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.

    Aliases: Mam-1 antibody, Mam1 antibody, MAML 1 antibody, Maml1 antibody, MAML1_HUMAN antibody, Mastermind like 1 antibody, Mastermind-like protein 1 antibody

    UniProt
    Q92585
    Pathways
    Notch Signalweg, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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