Complement C2 Antikörper (Middle Region)

Produktnummer ABIN5517107

Produktdetails anti-Complement C2 Antikörper

Target: Complement C2

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Complement C2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FILQDTKALH QVFEHMLDVS KLTDTICGVG NMSANASDQE RTPWHVTIKP

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human C2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 29 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Complement C2

Target: Complement C2

Andere Bezeichnung: C2 (Complement C2 Produkte)

Synonyme: CO2 antikoerper, complement C2 antikoerper, complement component 2 (within H-2S) antikoerper, C2 antikoerper

Hintergrund: Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.

Alias Symbols: CO2, ARMD14

Protein Size: 353

Gen-ID: 717

NCBI Accession: NP_000054

UniProt: A0A0G2JK28