FLT3 Antikörper (N-Term)
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- Target Alle FLT3 Antikörper anzeigen
- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FLT3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- FGTITNQDLP VIKCVLINHK NNDSSVGKSS SYPMVSESPE DLGCALRPQS
- Aufreinigung
- Affinity purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human FLT3
- Top Product
- Discover our top product FLT3 Primärantikörper
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anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 930-991) antibody
FLT3 Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 7B7C3 unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 62-295) antibodyFLT3 Reaktivität: Maus, Ratte WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) antibodyFLT3 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 334-543) antibodyFLT3 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 335-544) antibodyFLT3 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64), (N-Term) antibodyFLT3 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB01544 unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64) antibodyFLT3 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (FITC)FLT3 Reaktivität: Human FACS Wirt: Maus Monoclonal BV10A4 FITC
anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (PE)FLT3 Reaktivität: Human FACS Wirt: Maus Monoclonal BV10A4 PE
anti-Fms-Related tyrosine Kinase 3 (FLT3) (C-Term) antibodyFLT3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
- Andere Bezeichnung
- FLT3 (FLT3 Produkte)
- Synonyme
- FLT3 antikoerper, B230315G04 antikoerper, CD135 antikoerper, Flk-2 antikoerper, Flk2 antikoerper, Flt-3 antikoerper, Ly72 antikoerper, wmfl antikoerper, FLK-2 antikoerper, FLK2 antikoerper, STK1 antikoerper, fms related tyrosine kinase 3 antikoerper, FMS-like tyrosine kinase 3 antikoerper, fms-related tyrosine kinase 3 antikoerper, FLT3 antikoerper, Flt3 antikoerper
- Hintergrund
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This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
Alias Symbols: FLK2, STK1, CD135, FLK-2
Protein Size: 952 - Gen-ID
- 2322
- NCBI Accession
- NM_004119, NP_004110
- Pathways
- RTK Signalweg
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