CBX7 Antikörper (C-Term)

Produktnummer ABIN5516358

Produktdetails anti-CBX7 Antikörper

Target: CBX7 (Chromobox Homolog 7 (CBX7))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBX7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LSRKKFPPRG PNLESHSHRR ELFLQEPPAP DVLQAAGEWE PAAQPPEEEA

Produktmerkmale: This is a rabbit polyclonal antibody against CBX7. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CBX7

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CBX7

Target: CBX7 (Chromobox Homolog 7 (CBX7))

Andere Bezeichnung: CBX7 (CBX7 Produkte)

Synonyme: 1600014J01Rik antikoerper, AI851678 antikoerper, D15Ertd417e antikoerper, zgc:110152 antikoerper, chromobox 7 antikoerper, chromobox homolog 7a antikoerper, CBX7 antikoerper, Cbx7 antikoerper, cbx7a antikoerper

Hintergrund: CBX7 is a component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.

Protein Size: 251

Gen-ID: 23492

NCBI Accession: NP_783640

UniProt: O95931