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CYP27B1 Antikörper (C-Term)
CYP27B1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5516283
Produktdetails anti-CYP27B1 Antikörper
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Target
Alle CYP27B1 Antikörper anzeigen
CYP27B1
(Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1))
Bindungsspezifität
Alle Epitope für CYP27B1 Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für CYP27B1 Antikörper
Human
Wirt
Alle Wirte für CYP27B1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für CYP27B1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für CYP27B1 Antikörper
Dieser CYP27B1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für CYP27B1 Antikörper
Western Blotting (WB)
Sequenz
FRPARWLGEG PTPHPFASLP FGFGKRSCMG RRLAELELQM ALAQILTHFE
Aufreinigung
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CYP27B1
Top Product
Discover our top product CYP27B1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu CYP27B1
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Target
CYP27B1
(Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1))
Andere Bezeichnung
CYP27B1 (CYP27B1 Produkte )
Synonyme
cp2b antikoerper, cyp1 antikoerper, cyp1alpha antikoerper, cyp27b antikoerper, p450c1 antikoerper, pddr antikoerper, vdd1 antikoerper, vddr antikoerper, vddri antikoerper, vdr antikoerper, CP2B antikoerper, CYP1 antikoerper, CYP1alpha antikoerper, CYP27B antikoerper, P450c1 antikoerper, PDDR antikoerper, VDD1 antikoerper, VDDR antikoerper, VDDRI antikoerper, VDR antikoerper, Cyp40 antikoerper, Cp2b antikoerper, Cyp1 antikoerper, Cyp27b antikoerper, Pddr antikoerper, Vdd1 antikoerper, Vddr antikoerper, VddrI antikoerper, Vdr antikoerper, cytochrome P450 family 27 subfamily B member 1 antikoerper, cytochrome P450, family 27, subfamily B, polypeptide 1 antikoerper, cytochrome P450, family 27, subfamily b, polypeptide 1 antikoerper, cyp27b1 antikoerper, CYP27B1 antikoerper, Cyp27b1 antikoerper
Hintergrund
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I. Alias Symbols: VDR, CP2B, CYP1, PDDR, VDD1, VDDR, VDDRI, CYP27B, P450c1, CYP1alpha Protein Size: 508
Gen-ID
1594
NCBI Accession
NM_000785 , NP_000776
UniProt
O15528
Pathways
Metabolism of Steroid Hormones and Vitamin D
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