USP19 Antikörper (Middle Region)

Produktnummer ABIN5516193

Produktdetails anti-USP19 Antikörper

Target: USP19 (Ubiquitin Specific Peptidase 19 (USP19))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SQFTGYAQHD AQEFMAFLLD GLHEDLNRIQ NKPYTETVDS DGRPDEVVAE

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human USP19

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu USP19

Target: USP19 (Ubiquitin Specific Peptidase 19 (USP19))

Andere Bezeichnung: USP19 (USP19 Produkte)

Synonyme: wu:fc26a05 antikoerper, si:dkey-32e6.9 antikoerper, USP19 antikoerper, MGC145127 antikoerper, ZMYND9 antikoerper, 8430421I07Rik antikoerper, AI047774 antikoerper, Zmynd9 antikoerper, ubiquitin specific peptidase 19 antikoerper, universal stress protein antikoerper, ubiquitin carboxyl-terminal hydrolase 19 antikoerper, usp19 antikoerper, USP19 antikoerper, RR_RS18085 antikoerper, PTRG_09611 antikoerper, Usp19 antikoerper

Hintergrund: Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains.

Alias Symbols: ZMYND9

Protein Size: 1419

Gen-ID: 10869

NCBI Accession: NM_001199160, NP_001186089