RUNX3 Antikörper (C-Term)

Produktnummer ABIN5516157

Produktdetails anti-RUNX3 Antikörper

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RUNX3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PQNQSGPFQA NPSPYHLYYG TSSGSYQFSM VAGSSSGGDR SPTRMLASCT

Produktmerkmale: This is a rabbit polyclonal antibody against RUNX3. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RUNX3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RUNX3

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Andere Bezeichnung: RUNX3 (RUNX3 Produkte)

Synonyme: runxb antikoerper, RUNX3 antikoerper, CBFA3 antikoerper, frrunx3 antikoerper, runx3 antikoerper, aml2 antikoerper, cbfa3 antikoerper, pebp2ac antikoerper, AML2 antikoerper, Cbfa3 antikoerper, Pebp2a3 antikoerper, PEBP2aC antikoerper, runt-related transcription factor 3 antikoerper, runt related transcription factor 3 antikoerper, runt related transcription factor 3 L homeolog antikoerper, runx3 antikoerper, RUNX3 antikoerper, runx3.L antikoerper, Runx3 antikoerper

Hintergrund: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: RUNX3, AML2, CBFA3, PEBP2A3,

Protein Interaction Partner: Dlg4, UBC, PML, PIN1, NOTCH1, RBPJ, SIRT2, Cdk4, MDM2, EZH2, Vdr, SMURF2, SMURF1, HDAC9, SUV39H1, SMAD3, EP300, CBFB, SP110, HDAC5, HDAC4, HDAC2, HDAC1, TLE1, SMAD1, YAP1, SMAD5, SMAD2, PHB2,

Protein Size: 415

Gen-ID: 864

UniProt: Q13761