Fatty Acid Synthase Antikörper (Middle Region)

Produktnummer ABIN5516021

Produktdetails anti-Fatty Acid Synthase Antikörper

Target: Fatty Acid Synthase (FASN)

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fatty Acid Synthase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SENGNLVVSG KVYQWDDPDP RLFDHPESPT PNPTEPLFLA QAEVYKELRL

Produktmerkmale: This is a rabbit polyclonal antibody against FASN. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human FASN

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Andere Bezeichnung: FASN (FASN Produkte)

Synonyme: FAS antikoerper, OA-519 antikoerper, SDR27X1 antikoerper, FASN antikoerper, fj34h12 antikoerper, wu:fj34h12 antikoerper, Cgl0836 antikoerper, A630082H08Rik antikoerper, BcDNA:GH07626 antikoerper, BcDNA:gh07626 antikoerper, DM_7295848 antikoerper, Dmel\\CG3523 antikoerper, Fatty acid synthase antikoerper, anon-EST:Posey235 antikoerper, anon-EST:Posey43 antikoerper, anon-WO0138581.1 antikoerper, dFAS antikoerper, fas antikoerper, fatty acid synthase antikoerper, fatty acid synthase Fas antikoerper, type I polyketide synthase antikoerper, Fatty acid synthase Fas antikoerper, Fatty Acid SyNthase antikoerper, fatty-acid synthase antikoerper, fatty-acid synthase II antikoerper, fatty-acid synthase fas antikoerper, Fatty acid synthase 1 antikoerper, FASN antikoerper, fas antikoerper, Fasn antikoerper, BAD_RS01360 antikoerper, fasn antikoerper, fasn-1 antikoerper, NCgl0802 antikoerper, fasB antikoerper, MT2600 antikoerper, TBMG_01448 antikoerper, FASN1 antikoerper

Hintergrund: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Alias Symbols: FASN, FAS,

Protein Interaction Partner: UBC, FUS, HUWE1, SUMO3, SUMO2, STAU1, LGR4, SUMO1, MDM2, EED, KIAA1598, SIRT1, CAP1, TPM4, TPM3, FBXO6, YWHAQ, UBD, PHKG2, NPM1, LMNA, ILK, PRR12, VCAM1, NOS2, HSP90AB1, HSP90AA1, FN1, SMURF1, EIF4A3, PTPN11, MAGOH, TP53BP1, EMD, SHC1, AP2M1, CUL3, CDK2,

Protein Size: 2511

Gen-ID: 2194

NCBI Accession: NP_004095

UniProt: P49327

Pathways: AMPK Signaling