Fatty Acid Synthase Antikörper (AA 2212-2511)

Produktnummer ABIN3020991

Produktdetails anti-Fatty Acid Synthase Antikörper

Target: Fatty Acid Synthase (FASN)

Bindungsspezifität: AA 2212-2511

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fatty Acid Synthase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Sequenz: QQQTQLNLRS LLVNPEGPTL MRLNSVQSSE RPLFLVHPIE GSTTVFHSLA SRLSIPTYGL QCTRAAPLDS IHSLAAYYID CIRQVQPEGP YRVAGYSYGA CVAFEMCSQL QAQQSPAPTH NSLFLFDGSP TYVLAYTQSY RAKLTPGCEA EAETEAICFF VQQFTDMEHN RVLEALLPLK GLEERVAAAV DLIIKSHQGL DRQELSFAAR SFYYKLRAAE QYTPKAKYHG NVMLLRAKTG GAYGEDLGAD YNLSQVCDGK VSVHVIEGDH RTLLEGSGLE SIISIIHSSL AEPRVSVREG

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 2212-2511 of human Fatty Acid Synthase (FASN) (NP_004095.4).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Andere Bezeichnung: FASN (FASN Produkte)

Synonyme: FAS antikoerper, OA-519 antikoerper, SDR27X1 antikoerper, FASN antikoerper, fj34h12 antikoerper, wu:fj34h12 antikoerper, Cgl0836 antikoerper, A630082H08Rik antikoerper, BcDNA:GH07626 antikoerper, BcDNA:gh07626 antikoerper, DM_7295848 antikoerper, Dmel\\CG3523 antikoerper, Fatty acid synthase antikoerper, anon-EST:Posey235 antikoerper, anon-EST:Posey43 antikoerper, anon-WO0138581.1 antikoerper, dFAS antikoerper, fas antikoerper, fatty acid synthase antikoerper, fatty acid synthase Fas antikoerper, type I polyketide synthase antikoerper, Fatty acid synthase Fas antikoerper, Fatty Acid SyNthase antikoerper, fatty-acid synthase antikoerper, fatty-acid synthase II antikoerper, fatty-acid synthase fas antikoerper, Fatty acid synthase 1 antikoerper, FASN antikoerper, fas antikoerper, Fasn antikoerper, BAD_RS01360 antikoerper, fasn antikoerper, fasn-1 antikoerper, NCgl0802 antikoerper, fasB antikoerper, MT2600 antikoerper, TBMG_01448 antikoerper, FASN1 antikoerper

Hintergrund: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.,FAS,OA-519,SDR27X1,FASN,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,AMPK Signaling Pathway,Neuroscience,Cardiovascular,Lipids,Fatty Acids,FASN

Molekulargewicht: 273 kDa

Gen-ID: 2194

UniProt: P49327

Pathways: AMPK Signaling