CNTNAP2 Antikörper (Middle Region)

Produktnummer ABIN5515940

Produktdetails anti-CNTNAP2 Antikörper

Target: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNTNAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LRYNFQAPAT NARDSSSRVD NAPDQQNSHP DLAQEEIRFS FSTTKAPCIL

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CNTNAP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CNTNAP2

Target: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Andere Bezeichnung: CNTNAP2 (CNTNAP2 Produkte)

Synonyme: AUTS15 antikoerper, CASPR2 antikoerper, CDFE antikoerper, NRXN4 antikoerper, PTHSL1 antikoerper, 5430425M22Rik antikoerper, Caspr2 antikoerper, mKIAA0868 antikoerper, CASPR antikoerper, MGC145769 antikoerper, MGC147944 antikoerper, MGC147981 antikoerper, contactin associated protein like 2 antikoerper, contactin associated protein-like 2 antikoerper, contactin associated protein like 2b antikoerper, CNTNAP2 antikoerper, Cntnap2 antikoerper, cntnap2b antikoerper, cntnap2 antikoerper

Hintergrund: This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5 % of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation

Alias Symbols: CDFE, NRXN4, AUTS15, CASPR2, PTHSL1

Protein Size: 328

Gen-ID: 26047

NCBI Accession: NM_014141, NP_054860

UniProt: A0A0J9YYA0