CYP7A1 Antikörper (Middle Region)

Produktnummer ABIN5515922

Produktdetails anti-CYP7A1 Antikörper

Target: CYP7A1 (Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP7A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DPEIYPDPLT FKYDRYLDEN GKTKTTFYCN GLKLKYYYMP FGSGATICPG

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CYP7A1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CYP7A1

Target: CYP7A1 (Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))

Andere Bezeichnung: CYP7A1 (CYP7A1 Produkte)

Synonyme: CP7A antikoerper, CYP7 antikoerper, CYPVII antikoerper, CHAP antikoerper, CYP7S1 antikoerper, cyp7a1a antikoerper, zgc:63920 antikoerper, cytochrome P450 family 7 subfamily A member 1 antikoerper, cytochrome P450, family 7, subfamily a, polypeptide 1 antikoerper, cytochrome P450, family 7, subfamily A, polypeptide 1 antikoerper, cholesterol 7-alpha-hydroxylase antikoerper, CYP7A1 antikoerper, Cyp7a1 antikoerper, cyp7a1 antikoerper

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis.

Alias Symbols: CP7A, CYP7, CYPVII

Protein Size: 504

Gen-ID: 1581

NCBI Accession: NM_000780, NP_000771

UniProt: P22680

Pathways: Steroid Hormone Biosynthesis, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha