APOBEC3A Antikörper (Middle Region)

Produktnummer ABIN5515787

Produktdetails anti-APOBEC3A Antikörper

Target: APOBEC3A (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APOBEC3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PASGPRHLMD PHIFTSNFNN GIGRHKTYLC YEVERLDNGT SVKMDQHRGF

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human APOBEC3A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu APOBEC3A

Target: APOBEC3A (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A))

Andere Bezeichnung: APOBEC3A (APOBEC3A Produkte)

Synonyme: A3A antikoerper, ARP3 antikoerper, PHRBN antikoerper, bK150C2.1 antikoerper, APOBEC3A antikoerper, APOBEC3Z1 antikoerper, apolipoprotein B mRNA editing enzyme catalytic subunit 3A antikoerper, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A antikoerper, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3Z1 antikoerper, similar to ARP10 protein antikoerper, APOBEC3A antikoerper, APOBEC3Z1 antikoerper

Hintergrund: This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. The protein encoded by this gene is the same as that encoded by APOBEC3A, however, this gene is a hybrid gene that results from the deletion of approximately 29.5 kb of sequence between the APOBEC3A gene and the adjacent gene APOBEC3B. The breakpoints of the deletion are within the two genes, so the deletion hybrid is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B.

Protein Size: 199

Gen-ID: 100913187

NCBI Accession: NM_001193289, NP_001180218

UniProt: P31941