Neurexin 1 Antikörper (C-Term)

Produktnummer ABIN5515513

Produktdetails anti-Neurexin 1 Antikörper

Target: Neurexin 1 (NRXN1)

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neurexin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RDEGSYHVDE SRNYISNSAQ SNGAVVKEKQ PSSAKSSNKN KKNKDKEYYV

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NRXN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 29 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Neurexin 1

Target: Neurexin 1 (NRXN1)

Andere Bezeichnung: NRXN1 (NRXN1 Produkte)

Synonyme: Hs.22998 antikoerper, PTHSL2 antikoerper, SCZD17 antikoerper, CG7050 antikoerper, CT21808 antikoerper, Dmel\\CG7050 antikoerper, Nrx antikoerper, Nrx1 antikoerper, dnrx antikoerper, dnrx-1 antikoerper, nrx antikoerper, Nrxn1b antikoerper, NRXN1 antikoerper, Nrx-1 antikoerper, GB13455 antikoerper, GB18754 antikoerper, 1700062G21Rik antikoerper, 9330127H16Rik antikoerper, A230068P09Rik antikoerper, mKIAA0578 antikoerper, neurexin 1 antikoerper, Neurexin 1 antikoerper, neurexin I antikoerper, neurexin 1b antikoerper, neurexin 1a antikoerper, NRXN1 antikoerper, Nrx-1 antikoerper, Nrxn1 antikoerper, nrxn1 antikoerper, nrxn1b antikoerper, nrxn1a antikoerper

Hintergrund: This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission, and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. The RefSeq project has decided to create only a few representative transcript variants of the multitude that are possible. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2.

Alias Symbols: PTHSL2, SCZD17, Hs.22998

Protein Size: 396

Gen-ID: 9378

NCBI Accession: NM_004801, NP_620072

UniProt: A4FVB9

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development