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GAD Antikörper (N-Term)
GAD1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5515488
Produktdetails anti-GAD Antikörper
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Target
Alle GAD (GAD1) Antikörper anzeigen
GAD (GAD1)
(Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
Bindungsspezifität
Alle Epitope für GAD Antikörper
N-Term
Reaktivität
Alle Reaktivitäten für GAD Antikörper
Human
Wirt
Alle Wirte für GAD Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für GAD Antikörper
Polyklonal
Konjugat
Alle Konjugate für GAD Antikörper
Dieser GAD Antikörper ist unkonjugiert
Applikation
Alle Applikationen für GAD Antikörper
Western Blotting (WB)
Sequenz
CGFLQRTNSL EEKSRLVSAF KERQSSKNLL SCENSDRDAR FRRTETDFSN
Aufreinigung
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human GAD1
Top Product
Discover our top product GAD1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu GAD
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Target
GAD (GAD1)
(Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
Andere Bezeichnung
GAD1 (GAD1 Produkte )
Synonyme
CPSQ1 antikoerper, GAD antikoerper, SCP antikoerper, GAD-67 antikoerper, cpsq1 antikoerper, gad1 antikoerper, gad1-A antikoerper, gad67 antikoerper, GAD67 antikoerper, GAD1 antikoerper, GLUTAMATE DECARBOXYLASE antikoerper, GLUTAMATE DECARBOXYLASE 1 antikoerper, MKP11.30 antikoerper, MKP11_30 antikoerper, glutamate decarboxylase antikoerper, EP10 antikoerper, GAD25 antikoerper, GAD44 antikoerper, Gad-1 antikoerper, Gad67 antikoerper, glutamate decarboxylase 1 antikoerper, glutamate decarboxylase 1 L homeolog antikoerper, glutamate decarboxylase antikoerper, glutamate decarboxylase 1b antikoerper, GAD1 antikoerper, gad1.1.L antikoerper, GAD antikoerper, Gad1 antikoerper, gad1b antikoerper
Hintergrund
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. Alias Symbols: GAD, SCP, CPSQ1, Protein Size: 594
Gen-ID
2571
NCBI Accession
NM_000817 , NP_000808
UniProt
Q99259
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