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GAD Antikörper (N-Term)

GAD1 Reaktivität: Human WB, IHC, IHC (p), ICC, IF, IHC (fro), IHC (ff), IHC (wm) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855214
  • Target Alle GAD (GAD1) Antikörper anzeigen
    GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
    Bindungsspezifität
    • 15
    • 14
    • 11
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 92
    • 55
    • 51
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 81
    • 16
    • 3
    • 2
    Kaninchen
    Klonalität
    • 77
    • 25
    Polyklonal
    Konjugat
    • 56
    • 11
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GAD Antikörper ist unkonjugiert
    Applikation
    • 81
    • 32
    • 31
    • 13
    • 13
    • 12
    • 11
    • 10
    • 10
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Free Floating) (IHC (ff)), Immunohistochemistry (Whole Mount) (IHC (wm))
    Spezifität
    This antibody is specific for GAD67 protein, and it does not cross-react with GAD65 protein.
    Kreuzreaktivität
    Human, Maus, Ratte, Zebrafisch (Danio rerio)
    Produktmerkmale
    Rabbit Polyclonal antibody to GAD67 (glutamate decarboxylase 1 (brain, 67 kDa))
    GAD67 antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the N-terminus region of human GAD67. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product GAD1 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: human GAD1-transfected 293T

    Validation: Overexpression

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.22 mg/mL
    Buffer
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
    Andere Bezeichnung
    glutamate decarboxylase 1 (GAD1 Produkte)
    Synonyme
    CPSQ1 antikoerper, GAD antikoerper, SCP antikoerper, GAD-67 antikoerper, cpsq1 antikoerper, gad1 antikoerper, gad1-A antikoerper, gad67 antikoerper, GAD67 antikoerper, GAD1 antikoerper, GLUTAMATE DECARBOXYLASE antikoerper, GLUTAMATE DECARBOXYLASE 1 antikoerper, MKP11.30 antikoerper, MKP11_30 antikoerper, glutamate decarboxylase antikoerper, EP10 antikoerper, GAD25 antikoerper, GAD44 antikoerper, Gad-1 antikoerper, Gad67 antikoerper, glutamate decarboxylase 1 antikoerper, glutamate decarboxylase 1 L homeolog antikoerper, glutamate decarboxylase antikoerper, glutamate decarboxylase 1b antikoerper, GAD1 antikoerper, gad1.1.L antikoerper, GAD antikoerper, Gad1 antikoerper, gad1b antikoerper
    Hintergrund
    This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.

    Molekulargewicht
    67 kDa
    Gen-ID
    2571
    UniProt
    Q99259
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