PKLR Antikörper (N-Term)

Produktnummer ABIN5515040

Produktdetails anti-PKLR Antikörper

Target: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKLR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: TVDPAFRTRG NANTVWVDYP NIVRVVPVGG RIYIDDGLIS LVVQKIGPEG

Produktmerkmale: This is a rabbit polyclonal antibody against PKLR. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PKLR

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PKLR

Target: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Andere Bezeichnung: PKLR (PKLR Produkte)

Synonyme: PK1 antikoerper, PKL antikoerper, PKR antikoerper, PKRL antikoerper, RPK antikoerper, Pklg antikoerper, wu:fd15e01 antikoerper, wu:fi37e08 antikoerper, pk1 antikoerper, PKLR antikoerper, Pk-1 antikoerper, Pk1 antikoerper, R-PK antikoerper, pklr antikoerper, pyruvate kinase L/R antikoerper, pyruvate kinase, liver and RBC antikoerper, pyruvate kinase, liver and RBC L homeolog antikoerper, pyruvate kinase liver and red blood cell antikoerper, pyruvate kinase PKLR-like antikoerper, PKLR antikoerper, Pklr antikoerper, pklr antikoerper, pklr.L antikoerper, LOC100621940 antikoerper

Hintergrund: The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: PKLR, PK1, PKL,

Protein Interaction Partner: UBC, WWOX, SUMO4, CLEC4G, PCNA, OTUD5, USPL1, USP3, MYOC, KIF23, ARHGEF6, PXN, PAK1,

Protein Size: 574

Gen-ID: 5313

UniProt: P30613

Pathways: Ribonucleoside Biosynthetic Process