IBTK Antikörper (C-Term)

Produktnummer ABIN5514895

Produktdetails anti-IBTK Antikörper

Target: IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IBTK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GDIFLKEEIN MEQNHSETMF KKAKTKAKKK PRKRSDSSGG YNLSDIIQSP

Produktmerkmale: This is a rabbit polyclonal antibody against IBTK. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human IBTK

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IBTK

Target: IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))

Andere Bezeichnung: IBTK (IBTK Produkte)

Synonyme: IBTK antikoerper, fi40c08 antikoerper, wu:fi40c08 antikoerper, DKFZp468J085 antikoerper, BTBD26 antikoerper, BTKI antikoerper, RP1-93K22.1 antikoerper, 5430411K16Rik antikoerper, AA409502 antikoerper, mKIAA1417 antikoerper, inhibitor of Bruton tyrosine kinase antikoerper, inhibitor of Bruton agammaglobulinemia tyrosine kinase antikoerper, inhibitor of Bruton tyrosine kinase L homeolog antikoerper, IBTK antikoerper, ibtk antikoerper, Ibtk antikoerper, ibtk.L antikoerper

Hintergrund: Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Alias Symbols: IBTK, BTKI, KIAA1417,

Protein Interaction Partner: IGSF8, CD81, LAMTOR3, ITK, BTK, AKT1, PRKD1, PRKCG, PRKCE, PRKCD, PRKCB, PRKCA, PLCG1, CUL3, PPP1CA, UBC, RGS2,

Protein Size: 1353

Gen-ID: 25998

NCBI Accession: NP_056340

UniProt: Q9P2D0