NV18456 antikoerper, dad1 antikoerper, DAD1 antikoerper, ost2 antikoerper, DAD-1 antikoerper, si:ch211-9d9.5 antikoerper, OST2 antikoerper, AI323713 antikoerper, DEFENDER AGAINST APOPTOTIC DEATH 1 antikoerper, F3C3.14 antikoerper, F3C3_14 antikoerper, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 antikoerper, defender against cell death 1 antikoerper, hypothetical protein antikoerper, defender against cell death 1 S homeolog antikoerper, Defender against death (DAD family) protein antikoerper, false DAD1 antikoerper, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad-1 antikoerper, LOC100115214 antikoerper, DAD1 antikoerper, dad1 antikoerper, CC1G_00458 antikoerper, CpipJ_CPIJ003512 antikoerper, PGTG_09898 antikoerper, Dad1 antikoerper, dad1.S antikoerper, ATDAD1 antikoerper, fdad1 antikoerper, dad-1 antikoerper
Hintergrund
DAD1 is an essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis.