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DAD1 Antikörper

DAD1 Reaktivität: Human, Maus WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499706
  • Target Alle DAD1 Antikörper anzeigen
    DAD1 (Defender Against Cell Death 1 (DAD1))
    Reaktivität
    • 31
    • 18
    • 2
    Human, Maus
    Wirt
    • 44
    • 2
    Kaninchen
    Klonalität
    • 45
    • 1
    Polyklonal
    Konjugat
    • 12
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DAD1 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 18
    • 13
    • 13
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    DAD1 antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human DAD1.
    Aufreinigung
    Ion exchange chromatography
    Immunogen
    Murine DAD1 Peptide
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western Blot: 0.5 to 2 μg/mL. Despite its predicted molecular weight, DAD1 migrates at approx. 22 kDa in SDS-PAGE. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    DAD1 (Defender Against Cell Death 1 (DAD1))
    Andere Bezeichnung
    DAD1 (DAD1 Produkte)
    Synonyme
    NV18456 antikoerper, dad1 antikoerper, DAD1 antikoerper, ost2 antikoerper, DAD-1 antikoerper, si:ch211-9d9.5 antikoerper, OST2 antikoerper, AI323713 antikoerper, DEFENDER AGAINST APOPTOTIC DEATH 1 antikoerper, F3C3.14 antikoerper, F3C3_14 antikoerper, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 antikoerper, defender against cell death 1 antikoerper, hypothetical protein antikoerper, defender against cell death 1 S homeolog antikoerper, Defender against death (DAD family) protein antikoerper, false DAD1 antikoerper, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad-1 antikoerper, LOC100115214 antikoerper, DAD1 antikoerper, dad1 antikoerper, CC1G_00458 antikoerper, CpipJ_CPIJ003512 antikoerper, PGTG_09898 antikoerper, Dad1 antikoerper, dad1.S antikoerper, ATDAD1 antikoerper, fdad1 antikoerper, dad-1 antikoerper
    Hintergrund
    Defender of cell death 1 (DAD1) was initially discovered in BHK21 cells as a negative regulator of programmed cell death (1), a process important for normal organism development and tissue homeostasis (2). DAD1 was later shown to be a subunit of the mammalian oligosaccharyltransferase complex and is required for its function and structural integrity (3,4). Mice lacking DAD1 express abnormal N-linked glycoproteins and undergo increased apoptotic-associated embryonic death (5,6). Furthermore, overexpression of DAD1 mRNA is seen in some human hepatocellular carcinomas (7), indicating it may also play a role in carcinogenesis. It should be noted that DAD1 is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.Synonyms: DAD-1, OST2, defender against cell death 1, dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit DAD1, oligosaccharyl transferase subunit DAD1
    Gen-ID
    1603
    UniProt
    P61803
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