COL18A1 Antikörper (Middle Region)

Produktnummer ABIN5514687

Produktdetails anti-COL18A1 Antikörper

Target: COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Rind (Kuh), Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COL18A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VQLEARTPLP RGTDNEVAAL QPPVVQLHDS NPYPRREHPH PTARPWRADD

Homologie: Cow: 92%, Horse: 83%, Human: 100%, Pig: 83%, Rabbit: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against COIA1. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen for Anti-COL18A1 antibody is: synthetic peptide directed towards the Middle region of Human COIA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu COL18A1

Target: COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))

Andere Bezeichnung: COL18A1 (COL18A1 Produkte)

Synonyme: KNO antikoerper, KNO1 antikoerper, KS antikoerper, cb371 antikoerper, cb529 antikoerper, fc96d06 antikoerper, sb:cb529 antikoerper, wu:fb47h10 antikoerper, wu:fb77g12 antikoerper, wu:fc50f04 antikoerper, wu:fc96d06 antikoerper, wu:fk02h12 antikoerper, kno antikoerper, kno1 antikoerper, collagen type XVIII alpha 1 chain antikoerper, collagen type XVIII alpha 1 chain a antikoerper, collagen, type XVIII, alpha 1 antikoerper, collagen type XVIII alpha 1 antikoerper, COL18A1 antikoerper, col18a1a antikoerper, Col18a1 antikoerper, col18a1 antikoerper

Hintergrund: This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants.

Alias Symbols: KS, KNO, KNO1

Protein Interaction Partner: FUS, TUBG1, FBXO6, HNRNPD, TECPR1, GPC1, GPC4, KDR, FBLN2, ITGA5, MMP2, CTSL,

Protein Size: 1339

Gen-ID: 80781