COL18A1 Antikörper
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- Target Alle COL18A1 Antikörper anzeigen
- COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser COL18A1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- A synthetic peptide of human COL18A1 (NP_085059.2).
- Isotyp
- IgG
- Top Product
- Discover our top product COL18A1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
- Andere Bezeichnung
- COL18A1 (COL18A1 Produkte)
- Synonyme
- KNO antikoerper, KNO1 antikoerper, KS antikoerper, cb371 antikoerper, cb529 antikoerper, fc96d06 antikoerper, sb:cb529 antikoerper, wu:fb47h10 antikoerper, wu:fb77g12 antikoerper, wu:fc50f04 antikoerper, wu:fc96d06 antikoerper, wu:fk02h12 antikoerper, kno antikoerper, kno1 antikoerper, collagen type XVIII alpha 1 chain antikoerper, collagen type XVIII alpha 1 chain a antikoerper, collagen, type XVIII, alpha 1 antikoerper, collagen type XVIII alpha 1 antikoerper, COL18A1 antikoerper, col18a1a antikoerper, Col18a1 antikoerper, col18a1 antikoerper
- Hintergrund
- This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants.
- Molekulargewicht
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Observed_MW: 240 kDa
Calculated_MW: 135 kDa/154 kDa/178 kDa
- Gen-ID
- 80781
- UniProt
- P39060
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