ATP7B Antikörper (Middle Region)

Produktnummer ABIN5514518

Produktdetails anti-ATP7B Antikörper

Target: ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP7B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IIMSTLTLVV WIVIGFIDFG VVQRYFPNPN KHISQTEVII RFAFQTSITV

Homologie: Dog: 82%, Guinea Pig: 82%, Horse: 82%, Human: 100%, Mouse: 91%, Rabbit: 92%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against ATP7B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATP7B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ATP7B

Target: ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))

Andere Bezeichnung: ATP7B (ATP7B Produkte)

Synonyme: PWD antikoerper, WC1 antikoerper, WD antikoerper, WND antikoerper, Atp7a antikoerper, tx antikoerper, Hts antikoerper, PINA antikoerper, Wd antikoerper, ATP7B antikoerper, ATPase copper transporting beta antikoerper, ATPase, Cu++ transporting, beta polypeptide antikoerper, ATPase, Cu++ transporting, beta polypeptide (Wilson disease) antikoerper, copper-transporting ATPase 2 antikoerper, ATP7B antikoerper, Atp7b antikoerper, atp7b antikoerper, LOC592143 antikoerper

Hintergrund: This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).

Alias Symbols: WD, PWD, WC1, WND

Protein Size: 676

Gen-ID: 540

NCBI Accession: NM_000053, NP_000044

UniProt: P35670

Pathways: Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process