ALPL Antikörper (Middle Region)

Produktnummer ABIN5514493

Produktdetails anti-ALPL Antikörper

Target: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALPL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HATPSAAYAH SADRDWYSDN EMPPEALSQG CKDIAYQLMH NIRDIDVIMG

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ALPL

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ALPL

Target: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Andere Bezeichnung: ALPL (ALPL Produkte)

Synonyme: ALP antikoerper, iap antikoerper, alpl antikoerper, AP-TNAP antikoerper, APTNAP antikoerper, HOPS antikoerper, TNAP antikoerper, TNSALP antikoerper, Akp-2 antikoerper, Akp2 antikoerper, PHOA antikoerper, TNS-AP antikoerper, alkaline phosphatase, liver/bone/kidney L homeolog antikoerper, alkaline phosphatase, liver/bone/kidney antikoerper, alkaline phosphatase, intestinal, gene 2 antikoerper, alkaline phosphatase, liver/bone/kidney pseudogene antikoerper, alpl.L antikoerper, ALPL antikoerper, alpi.2 antikoerper, LOC100031702 antikoerper, Alpl antikoerper

Hintergrund: This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects.

Alias Symbols: HOPS, TNAP, APTNAP, TNSALP, AP-TNAP,

Protein Size: 524

Gen-ID: 249

NCBI Accession: NM_000478, NP_000469

UniProt: P05186