ALPL Produkte
(Alkaline Phosphatase, Liver/bone/kidney (ALPL))
Kategorien
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization\; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010].
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Ausgewählte ALPL Kategorien
ALPL Antikörper
High quality antibodies with extensive validation data.
ALPL ELISA Kits
Reliable ELISA kits for a wide range of species.
ALPL Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ALPL Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7433150
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS
Validierungen
- (2)
- (5)
Kat. Nr.
ABIN969500
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Cow, Human
Applikation
IHC, StM
Validierungen
- (5)
Kat. Nr.
ABIN6939448
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene ALPL ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6963030
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rabbit
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6973340
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (6)
- (1)
Kat. Nr.
ABIN6960610
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ALPL Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7121791
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1344937
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1344939
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ALPL Produkten
: "Effect of herbal extract Eurycoma longifolia (Physta®) on female reproductive hormones and bone biochemical markers: an ovariectomised rat model study." in: BMC complementary medicine and therapies, Vol. 20, Issue 1, pp. 31, (2020) (PubMed).: "Smart Nanosacrificial Layer on the Bone Surface Prevents Osteoporosis through Acid-Base Neutralization Regulated Biocascade Effects." in: Journal of the American Chemical Society, Vol. 142, Issue 41, pp. 17543-17556, (2020) (PubMed).
: "Mesenchymal Precursor Cells in Adult Nerves Contribute to Mammalian Tissue Repair and Regeneration." in: Cell stem cell, Vol. 24, Issue 2, pp. 240-256.e9, (2019) (PubMed).
: "Activation of cancer-related and mitogen-activated protein kinase signaling pathways in human mature osteoblasts isolated from patients with type 2 diabetes." in: Bone reports, Vol. 10, pp. 100199, (2019) (PubMed).
: "Growth Factor Screening in Dystrophic Muscles Reveals PDGFB/PDGFRB-Mediated Migration of Interstitial Stem Cells." in: International journal of molecular sciences, Vol. 20, Issue 5, (2019) (PubMed).
: "Reduced Basal Nitric Oxide Production Induces Precancerous Mammary Lesions via ERBB2 and TGFβ." in: Scientific reports, Vol. 9, Issue 1, pp. 6688, (2019) (PubMed).
: "Silent Mating Type Information Regulation 2 Homolog (SIRT1) Influences Osteogenic Proliferation and Differentiation of MC3T3-E1 Cells via Regulation of miR-132-3p." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 25, pp. 2289-2295, (2019) (PubMed).
: "Osteosarcoma cell-derived exosomes affect tumor microenvironment by specific packaging of microRNAs." in: Carcinogenesis, (2019) (PubMed).
: "Protective Effects of Melon Extracts on Bone Strength, Mineralization, and Metabolism in Rats with Ovariectomy-Induced Osteoporosis." in: Antioxidants (Basel, Switzerland), Vol. 8, Issue 8, (2019) (PubMed).
: "FGF23 is synthesised locally by renal tubules and activates injury-primed fibroblasts." in: Scientific reports, Vol. 7, Issue 1, pp. 3345, (2018) (PubMed).
Synonyme und alternative Namen zu ALPL
alkaline phosphatase, liver/bone/kidney L homeolog (alpl.L), alkaline phosphatase, liver/bone/kidney (ALPL), alkaline phosphatase, intestinal, gene 2 (alpi.2), alkaline phosphatase, liver/bone/kidney pseudogene (LOC100031702), alkaline phosphatase, liver/bone/kidney (Alpl), Akp-2, Akp2, ALP, alpl, AP-TNAP, APTNAP, HOPS, iap, PHOA, TNAP, TNS-AP, TNSALPBezeichner auf Proteinebene für ALPL
- tissue-nonspecific alkaline phosphatase
- alkaline phosphatase, tissue-nonspecific isozyme
- tissue non-specific alkaline phosphatase
- alkaline phosphatase, liver/bone/kidney
- alkaline phosphatase, tissue-nonspecific isozyme-like
- alkaline phosphatase liver/bone/kidney isozyme
- alkaline phosphomonoesterase
- glycerophosphatase
- liver/bone/kidney-type alkaline phosphatase
- tissue-nonspecific ALP
- alkaline phosphatase 2, liver
- AP-TNAP
- TNSALP
- Tissue-nonspecific ALP alkaline phosphatase
- alkaline phosphatase tissue non-specific isoform
- liver/bone/kidney isozyme
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