ALS2 Produkte
(Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
Kategorien
The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
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Ausgewählte ALS2 Kategorien
ALS2 Antikörper
High quality antibodies with extensive validation data.
Empfohlene ALS2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (4)
Kat. Nr.
ABIN6136830
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7143956
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN390394
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene ALS2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1344948
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ALS2 Produkten
: "Rab5 and Alsin regulate stress-activated cytoprotective signaling on mitochondria." in: eLife, Vol. 7, (2018) (PubMed).: "Are alsin and spartin novel interaction partners?" in: Biochemical and biophysical research communications, Vol. 427, Issue 1, pp. 1-4, (2012) (PubMed).
: "The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis." in: Nature genetics, Vol. 29, Issue 2, pp. 160-5, (2001) (PubMed).
Synonyme und alternative Namen zu ALS2
amyotrophic lateral sclerosis 2a (juvenile) (als2a), alsin (CpipJ_CPIJ008258), alsin (CpipJ_CPIJ008260), ALS2, alsin Rho guanine nucleotide exchange factor (ALS2), ALS2, alsin Rho guanine nucleotide exchange factor (Als2), amyotrophic lateral sclerosis 2 (juvenile) (Als2), amyotrophic lateral sclerosis 2 (juvenile) (ALS2), 3222402C23Rik, 9430073A21Rik, als2, ALS2CR6, Als2cr6, Alsin, ALSJ, IAHSP, mKIAA1563, PLSJ, si:dkey-33m14.1Bezeichner auf Proteinebene für ALS2
- alsin 2
- amyotrophic lateral sclerosis 2 (juvenile)
- alsin
- alsin-like
- amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein
- amyotrophic lateral sclerosis 2 protein
- amyotrophic lateral sclerosis 2 protein homolog
- amyotrophic lateral sclerosis protein 2 homolog
- amyotrophic lateral sclerosis 2 (juvenile) homolog
Haben Sie etwas anderes gesucht?
- ALR2
- ALPPL2
- ALPL
- ALPK3
- ALPK2
- ALPK1
- alphaHBDH
- alpha-Trichosanthin
- alpha-Thrombin
- alpha-N-Acetylgalactosaminide alpha-2,6-Sialyltransferase 3
- alpha-Mannosidase II
- alpha-L-Fucosidase
- alpha-Endorphin
- Alpha-amylase 1
- alpha-1,4-Glucan-Protein Synthase
- alpha Tubulin
- alpha Taxilin
- alpha KGDHC
- alpha Fetoprotein
- alpha Adducin
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