DOK1 Antikörper (pSer450)

Produktnummer ABIN548455

Produktdetails anti-DOK1 Antikörper

Target: DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))

Bindungsspezifität: pSer450

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic phosphopeptide of DOK1.

Spezifität: This sequence is conserved in Dok1 from rat (Ser-449) and mouse (Ser-451). The site is not conserved in other Dok family members.

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Antibody Reactive Against Synthetic Peptide.

Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S450 of human DOK1.

Anwendungsinformationen

Applikationshinweise: ELISA (1:2000)
Western Blot (1:500)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (50 % glycerol, 1 mg/mL BSA, 0.05 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-DOK1 Antikörper (ABIN548455)

Woodring, Meisenhelder, Johnson, Zhou, Field, Shah, Bladt, Pawson, Niki, Pandolfi, Wang, Hunter: "c-Abl phosphorylates Dok1 to promote filopodia during cell spreading." in: The Journal of cell biology, Vol. 165, Issue 4, pp. 493-503, (2004) (PubMed).

Lee, Andrieu, Saltel, Destaing, Auclair, Pouchkine, Michelon, Salaun, Kobayashi, Jurdic, Kieff, Sylla: "IkappaB kinase beta phosphorylates Dok1 serines in response to TNF, IL-1, or gamma radiation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 50, pp. 17416-21, (2004) (PubMed).

Kashige, Carpino, Kobayashi: "Tyrosine phosphorylation of p62dok by p210bcr-abl inhibits RasGAP activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 5, pp. 2093-8, (2000) (PubMed).

Details zu DOK1

Target: DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))

Andere Bezeichnung: DOK1 / p62 dok (DOK1 Produkte)

Synonyme: P62DOK antikoerper, Dok-1 antikoerper, AW557123 antikoerper, p62DOK antikoerper, dok1 antikoerper, zgc:76914 antikoerper, docking protein 1 antikoerper, docking protein 1b antikoerper, DOK1 antikoerper, Dok1 antikoerper, dok1b antikoerper

Gen-ID: 1796