DOK1 Antikörper (pTyr362)

Produktnummer ABIN7138991

Produktdetails anti-DOK1 Antikörper

Target: DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))

Bindungsspezifität: pTyr362

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 362 (P-I-Y(p)-D-E) derived from Human p62Dok.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000, IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DOK1

Target: DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))

Andere Bezeichnung: DOK1 (DOK1 Produkte)

Synonyme: P62DOK antikoerper, Dok-1 antikoerper, AW557123 antikoerper, p62DOK antikoerper, dok1 antikoerper, zgc:76914 antikoerper, docking protein 1 antikoerper, docking protein 1b antikoerper, DOK1 antikoerper, Dok1 antikoerper, dok1b antikoerper

Hintergrund:

Background:

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

Zhou Songyang, et al. (2001) J. Biol. Chem , 276: 2459 - 2465.
Jean-Guy N

Aliases: Docking protein 1 62kD antibody, Docking protein 1 antibody, DOK 1 antibody, DOK1 antibody, DOK1_HUMAN antibody, Downstream of tyrosine kinase 1 antibody, p62(dok) antibody, P62DOK antibody, pp62 antibody

UniProt: Q99704